AlphaFold Sovereign

Verified Integration

Author: @qualified•Category: ServerApplication

GitHub Repository

JSON-RPC 2.0

Protocol Standard

Sub-second

Execution Latency

Active

Operational Status

Client Configuration

— Connect AlphaFold Sovereign to Claude Desktop or Cursor in seconds

{
  "mcpServers": {
    "alphafold-sovereign": {
      "command": "npx",
      "args": [
        "-y",
        "@modelcontextprotocol/server-alphafold-sovereign"
      ],
      "env": {}
    }
  }
}

Paste into ~/Library/Application Support/Claude/claude_desktop_config.json (macOS) or %APPDATA%\Claude\claude_desktop_config.json (Windows).

Architecture & Capabilities

System Overview

Composes AlphaFold DB and eight public biomedical data sources into a local SQLite knowledge graph via Model Context Protocol tool calls.

Indexed Date

7/21/2026

License

Open Source

Protocol Layer

stdio / SSE RPC

Frequently Asked Questions

Architecture and operational details for AlphaFold Sovereign

It wraps AlphaFold DB, MONDO, HPO, Open Targets, ClinVar, gnomAD, DisGeNET, ChEMBL, and Ensembl, making their data accessible through a unified set of MCP tool calls.

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