AutoPVS1 Link
Verified IntegrationClient Configuration
— Connect AutoPVS1 Link to Claude Desktop or Cursor in seconds{
"mcpServers": {
"autopvs1-link": {
"command": "npx",
"args": [
"-y",
"@modelcontextprotocol/server-autopvs1-link"
],
"env": {}
}
}
}~/Library/Application Support/Claude/claude_desktop_config.json (macOS) or %APPDATA%\Claude\claude_desktop_config.json (Windows).System Overview
Provides automated ACMG PVS1 loss-of-function evidence for sequence and copy-number variants, serving as a typed tool for LLM agents.
7/22/2026
Open Source
stdio / SSE RPC
Frequently Asked Questions
Architecture and operational details for AutoPVS1 Link
It employs robust scraping with parsers pinned to HTML fixtures, ensuring that changes to the upstream AutoPVS1 website fail CI rather than causing silent data errors. It also implements caching (default 24h TTL) and a 1.0s rate-limiting delay to prevent overwhelming the AutoPVS1 service.
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