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GnomAD

Verified Integration
Author: @shukwong•Category: ServerApplication
GitHub Repository
JSON-RPC 2.0
Protocol Standard
Sub-second
Execution Latency
Active
Operational Status
Tags:#Claude#Search#Database#API#Git#AI#GitHub#Node.js

Client Configuration

— Connect GnomAD to Claude Desktop or Cursor in seconds
{
  "mcpServers": {
    "gnomad": {
      "command": "npx",
      "args": [
        "-y",
        "@modelcontextprotocol/server-gnomad"
      ],
      "env": {}
    }
  }
}
Paste into ~/Library/Application Support/Claude/claude_desktop_config.json (macOS) or %APPDATA%\Claude\claude_desktop_config.json (Windows).
Architecture & Capabilities

System Overview

Provides access to the gnomAD GraphQL API for AI assistants.

Indexed Date

7/23/2026

License

Open Source

Protocol Layer

stdio / SSE RPC

Frequently Asked Questions

Architecture and operational details for GnomAD

You can retrieve detailed gene information (including constraint scores like pLI and LOEUF), specific genetic variants and their population frequencies, allele frequencies across diverse populations, and find variants within specified genomic regions. It also supports structural and mitochondrial variants.

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