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gnomAD

Verified Integration
Author: @pipeworx-io•Category: ServerApplication
GitHub Repository
JSON-RPC 2.0
Protocol Standard
Sub-second
Execution Latency
Active
Operational Status
Tags:#Claude#Search#Database#API#Git#AI#GitHub#Node.js

Client Configuration

— Connect gnomAD to Claude Desktop or Cursor in seconds
{
  "mcpServers": {
    "gnomad-1": {
      "command": "npx",
      "args": [
        "-y",
        "@modelcontextprotocol/server-gnomad-1"
      ],
      "env": {}
    }
  }
}
Paste into ~/Library/Application Support/Claude/claude_desktop_config.json (macOS) or %APPDATA%\Claude\claude_desktop_config.json (Windows).
Architecture & Capabilities

System Overview

Provides access to the Broad Institute gnomAD genomic variant database via a GraphQL interface.

Indexed Date

7/23/2026

License

Open Source

Protocol Layer

stdio / SSE RPC

Frequently Asked Questions

Architecture and operational details for gnomAD

While you can query variants within any specified genomic region, it is recommended to keep region queries to 25kb or less for optimal performance and efficiency when accessing data through the gnomAD tool.

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