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Helix

Verified Integration
Author: @coindef•Category: ServerApplication
GitHub Repository
JSON-RPC 2.0
Protocol Standard
Sub-second
Execution Latency
Active
Operational Status
Tags:#Claude#Search#Database#API#Git#AI#GitHub#Node.js

Client Configuration

— Connect Helix to Claude Desktop or Cursor in seconds
{
  "mcpServers": {
    "helix-2": {
      "command": "npx",
      "args": [
        "-y",
        "@modelcontextprotocol/server-helix-2"
      ],
      "env": {}
    }
  }
}
Paste into ~/Library/Application Support/Claude/claude_desktop_config.json (macOS) or %APPDATA%\Claude\claude_desktop_config.json (Windows).
Architecture & Capabilities

System Overview

Enables reproducible gene-editing design through a declarative DSL and compiler, integrated with LLM agents and an MCP server for safe AI-driven operation.

Indexed Date

7/23/2026

License

Open Source

Protocol Layer

stdio / SSE RPC

Frequently Asked Questions

Architecture and operational details for Helix

Yes, Helix offers injectable backends. This unique feature allows users to swap built-in heuristics for real bioinformatics tools (like Cas-OFFinder, inDelphi, or Ensembl/NCBI) by simply editing the spec, without modifying the core code.

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